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15 Model Years

RX 350 - 15 Model Years

The Lexus RX 350 is an SUV. The 2021 RX 350 starts at $45,070 (MSRP), with a destination charge of $1,025. It gets EPA-estimated 22-23 MPG combined.
Good Fit For
Towing

Towing vehicles can tow a minimum of 2,000 pounds (see specifications for maximum). May require specific trim level and/or optional features.

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Luxury Shoppers

Luxury vehicles include all models from dedicated luxury brands plus luxurious models selected by our editors.

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Small Families

Small Family vehicles include mid-size and larger sedans, hatchbacks, wagons, SUVs and minivans with four doors and five seats.

2007–2021 RX 350 Generation, 2021 Lexus RX 350 model shown Showing the 2021 Lexus RX 350
MSRP Range $45,070–$52,350
Consumer Rating
(5.0) 2 reviews
Combined MPG 22-23
Body Styles SUV
  • MSRP Range $44,150–$51,750
  • Consumer Rating
    (4.9) 64 reviews
  • Combined MPG 22-23
  • Body Styles SUV
  • MSRP Range $36,729–$64,268
  • Consumer Rating Not yet rated
  • Combined MPG 22-23
  • Body Styles SUV
Notable Features in 2019
  • Gas (RX 350) and hybrid (RX 450h) models
  • Three-row L version available
  • Lexus Safety System Plus standard
  • Eight-speed automatic standard
  • Performance-oriented F Sport model available
  • Head-up display available
  • MSRP Range $31,839–$45,459
  • Consumer Rating
    (4.7) 86 reviews
  • Combined MPG 22-23
  • Body Styles SUV
Notable Features in 2018
  • Three-row L version now available
  • Gas (RX 350) and hybrid (RX 450h) models
  • Lexus Safety System Plus standard
  • Eight-speed automatic standard
  • Performance-oriented F Sport model available
  • Head-up display available
  • Current List Price $28,831–$42,075
  • Consumer Rating
    (4.6) 238 reviews
  • Combined MPG 22-23
  • Body Styles SUV
Notable Features in 2017
  • Lexus Safety System Plus now standard
  • Five-seat midsize luxury SUV
  • Eight-speed automatic transmission standard
  • Regular (RX 350) and hybrid (RX 450h) versions
  • Performance-oriented F Sport model available
  • Head-up display available
  • Current List Price $25,831–$38,459
  • Consumer Rating
    (4.1) 115 reviews
  • Combined MPG 22-23
  • Body Styles SUV
Notable Features in 2016
  • Restyled 5-seat midsize luxury SUV
  • 8-speed transmission now standard
  • New interior color choices
  • Regular (RX 350) and hybrid (RX 450h) versions
  • F Sport performance-oriented model available
  • FWD or AWD
  • Head-up display available
  • Current List Price $18,275–$30,327
  • Consumer Rating
    (4.7) 172 reviews
  • Combined MPG 21
  • Body Styles SUV
Notable Features in 2015
  • Stereo with 7-inch screen and backup camera now standard
  • Regular (RX 350) and hybrid (RX 450h) versions
  • F Sport performance-oriented model available
  • FWD or AWD
  • Head-up display available
  • Current List Price $16,117–$26,625
  • Consumer Rating
    (4.6) 58 reviews
  • Combined MPG 21
  • Body Styles SUV
Notable Features in 2014
  • Newly available Apple Siri Eyes Free Mode
  • Regular (RX 350) and hybrid (RX 450h) versions
  • F Sport performance-oriented model
  • FWD or AWD
  • Available head-up display
  • Current List Price $14,726–$24,950
  • Consumer Rating
    (4.6) 112 reviews
  • Combined MPG 21
  • Body Styles SUV
Notable Features in 2013
  • New front-end styling
  • New F Sport performance version
  • Regular (RX 350) and hybrid (RX 450h) versions
  • FWD or AWD
  • Optional head-up display
  • 10 airbags
  • Current List Price $11,807–$22,351
  • Consumer Rating
    (4.9) 70 reviews
  • Combined MPG 21
  • Body Styles SUV
Notable Features in 2012
  • 10 airbags
  • FWD or AWD
  • Optional wide-view side monitor
  • Optional head-up display
  • RX now takes regular gas
  • Current List Price $10,423–$20,635
  • Consumer Rating
    (4.6) 69 reviews
  • Combined MPG 21
  • Body Styles SUV
Notable Features in 2011
  • Brake override system
  • 10 airbags
  • FWD or AWD
  • Optional wide-view side monitor
  • Optional head-up display
  • Current List Price $10,156–$18,676
  • Consumer Rating
    (4.7) 122 reviews
  • Combined MPG 21
  • Body Styles SUV
Notable Features in 2010
  • Redesigned for 2010
  • 10 airbags
  • FWD or AWD
  • Optional wide-view side monitor
  • Optional head-up display
  • Current List Price $6,117–$16,669
  • Consumer Rating
    (4.9) 70 reviews
  • Combined MPG 19-20
  • Body Styles SUV
  • Current List Price $5,595–$14,647
  • Consumer Rating
    (4.5) 75 reviews
  • Combined MPG 19-20
  • Body Styles SUV
  • Current List Price $5,377–$12,881
  • Consumer Rating
    (4.6) 69 reviews
  • Combined MPG 21-22
  • Body Styles SUV

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